Publications
2024
Janic A, Abad E and Amelio I. “Decoding p53 tumour suppression: A crosstalk between genomic stability and epigenetic control?”
Cell Death Differentiation 2024 in press
2023
Suciu I, Delp J, Gutbier S, Suess J, Henschke L, Celardo I, Mayer TU, Amelio I and Leist M. “Definition of the neurotoxicity-associated metabolic signature triggered by berberine and other respiratory chain inhibitors.”
Antioxidants 2023 Dec 28;13(1):49
Butera A, Smirnova L, Ferrando-May E, Hartung T, Brunner T, Leist M and Amelio I. “Deconvoluting gene and environment interactions to develop an “epigenetic score meter” of disease.”
EMBO Molecular Medicine 2023 Sep 11;15(9):e18208
Suciu I, Pamies D, Peruzzo R, Wirtz PH, Smirnova L, Pallocca G, Hauck C, Cronin MTD, Hengstler JG, Brunner T, Hartung T, Amelio I, Leist M. “G × E interactions as a basis for toxicological uncertainty”
Arch Toxicology 2023 Jul;97(7):2035-2049
Butera A and Amelio I. “Healthy vs bad lifestyle… or just get the right genetic mutations.”
Cell Cycle 2023 Jun;22(11):1353-1356
Vitale I, Pietrocola F, Guilbaud E, Aaronson SA, Abrams JM, Adam D, Agostini M, Agostinis P, Alnemri ES, Altucci L, Amelio I, […], Piacentini M, Kroemer G and Galluzzi L. “Apoptotic cell death in disease-Current understanding of the NCCD 2023”
Cell Death & Differentiation 2023 Apr 26;1-58
Suciu I, Delp J, Gutbier S, Uckert AK, Spreng AS, Eberhard P, Karreman C, Schreiber F, Madjar K, Rahnenfurer J, Celardo I, Amelio I, Leist M. “Dynamic Metabolic and Transcriptional Responses of Proteasome-Inhibited Neurons”
Antioxidants 2023 Jan 10;12(1):164.
2022
Panatta E, Butera A, Celardo I, Leist M, Mauriello A, Melino G, Amelio I. “p53 regulates expression of nuclear envelope components in cancer cells”
Biology Direct 2022 Dec 2;17(1):38.
Panatta E, Butera A, Mammarella E, Pitolli C, Leist M, Mauriello A, Knight A, Melino G, Amelio I. “Metabolic control by p53 prevents R-loop-associated genomic instability”
Cell Reports 2022 Nov 1;41(5):111568.
[Article featured in the journal Cover page]
Caporali S, Butera A, Amelio I. “BAP1 in cancer: epigenetic stability and genome integrity”.
Discover Oncology 2022 Nov 1;13(1):117.
Ganini C, Montanaro M, Scimeca M, Palmieri G, Anemona L, Concetti L, Melino G, Bove P, Amelio I, Candi E, Mauriello A. “No Time to Die: How Kidney Cancer Evades Cell Death”
IJMS 2022 May 31;23(11):6198.
Butera A, Roy M, Zampieri C, Mammarella E, Panatta E, Melino G, D’Alessandro A§, Amelio I§. “p53-driven lipidome directs non-cell-autonomous lysophospholipids in pancreatic cancer”
Biology Direct 2022 Mar 8;17(1):6
Zampieri C, Panatta E, Corbo V, Mauriello A, Melino G, Amelio I. “p53 mutations define chromatin landscape to confer drug tolerance in pancreatic cancer”
Molecular Oncology 2022 Mar;16(6):1259-1271.
[Article featured in the journal Cover page]
Selected Publications until 2021
Lena AM, Rossi V, Osterburg S, Smirnov A, Tuppi M, Cappello A, Amelio I, Dotsch V, De Felici M, Klinger F, Valensise F, Melino G and Candi E. “The C-terminus of p63 is essential for murine oocyte integrity”
Nature Communications 2021, Jan 15;12(1):383.
Amelio I§, Panatta E, Niklison-Chirou MV, Steiner J, Agostini M, Anemona L, Morone N, Knight RA, and Melino G.§ “The C-terminus of p73 is essential for hippocampal development”
PNAS-USA 2020 Jul 7;117(27):15694-15701 (§corresponding authors).
Amelio I§, Mancini M, Petrova V, Cairns R, [et al.], Mak TW, Melino G§. “p53 mutants co-operate with HIF-1 in transcriptional regulation of extracellular matrix components to promote tumour progression”.
PNAS-USA 2018 Nov 13;115(46): E10869-E10878. (§corresponding authors).
Marini A, Rotblat B, Sbarrato T, Niklison MV, Knight J, Dudek K, Jones C, Bushell M, Knight RA, Amelio I, Willis AE, Melino G. “TAp73 contributes to the oxidative stress response by regulating protein synthesis”.
PNAS-USA 2018 Jun 12;115(24):6219-6224.
Amelio I & Melino G. “The p53 family and HIFs: determinants of cancer progression”.
Trends in Biochemical Science 2015, 40(8):425-34.
Amelio I, Inoue S, Markert E, Levine A, Knight RA, Mak TW and Melino G. “TAp73 opposes tumour angiogenesis promoting Hypoxia Inducible Factor degradation”.
PNAS-USA 2015, 112(1):226-31.
Inoue S, Tomasini R, Rufini A, Elia AJ, Agostini M, Amelio I, [et al.], and Mak TW. “TAp73 is required for spermatogenesis and the maintenance of male fertility.”
PNAS-USA 2014, 111(5):1843-8.
Amelio I, Lena AM, Viticchiè G, Shalom-Feuerstein R, Fortunato C, [et al.] Candi E and Melino G. “miR-24 promotes epidermal differentiation by controlling actin adhesion and cell migration”.
The Journal of Cell Biology 2012, 199(2):347-63.