Current news

New research gives unprecedented view of colorectal cancer genetic makeup

In a recent study published in Nature (doi: 10.1038/s41586-024-07747-9), a group of researchers provided a comprehensive genomic characterization of colorectal carcinoma (CRC), a type of cancer that starts in the colon or rectum, through whole-genome sequencing (WGS) of 2,023 samples, identifying novel driver genes, molecular subgroups, and potential clinical implications.

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A good first impression

A collaborative research environment is key for establishing a new research group: insights from bioinformatician Andreas Gruber, funded within the framework of the Joint Federal Government-Länder Tenure-Track Programme.

Launch of the NFG027 Junior Research Group

Currently available therapies are mostly designed for the "average" patient and neglect patient-to-patient heterogeneity. The aim of the project is to use artificial intelligence approaches, which are already changing the professional world in many ways, to discover previously unknown molecular signatures and to unlock their biomarker potential for personalized medicine.

Introduction at the Lindau Nobel Laureate Meeting

After the Rector of the University of Konstanz, Prof. Dr. Katharina Holzinger, welcomed the guests, Prof. Dr. Liane Wörner elaborated on the research objective and the basic idea of the Centre for Human | Data | Society. Jun-Prof. Dr. Andreas Gruber (member of the CHDS) also presented some of his CHDS-related research projects. With Eirliani Abdul Rahman (scholarship holder), Dr. Svenja Behrendt and Dr. Alexandra Windsberger, further members of the Centre were able to present their research…

Interactions between RNA viruses and human RNA-binding proteins

Viruses are intracellular parasites that need their host cell to reproduce. Consequently, they have evolved numerous mechanisms to exploit the molecular machinery of their host cells, including the broad spectrum of host RNA-binding proteins (RBPs). To shed light on the interaction landscape of RNA viruses with human host cell RBPs at a large scale, the Gruber lab and collaborators have analysed single-stranded RNA (ssRNA) viral genome sequences, including SARS‑CoV‑2...