* shared corresponding authorship
2023
Mao, Z., J. Fleming, O. Mayans, J. Frey, D. Schleheck, B. Schink and N. Müller. 2023.
AMP-dependent phosphite dehydrogenase (ApdA), a phosphorylating enzyme in dissimilatory phosphite oxidation.
PNAS. 120: e2309743120. DOI: 10.1073/pnas.2309743120
Ye, H., S. Borusak, C. Eberl, J. Krasenbrink, A.S. Weiss, S.-C. Chen, B.T. Hanson, B. Hausmann, C.W. Herbold, M. Pristner, B. Zwirzitz, B. Warth, P. Pjevac, D. Schleheck, B. Stecher and A. Loy. 2023.
Ecophysiology and interactions of a novel taurine-respiring bacterium in the mouse gut.
Nature Communications. 14: 5533. DOI: 10.1038/s41467-023-41008-z
Mao, Z., N. Müller, S. Borusak, D. Schleheck and B. Schink. 2023.
Anaerobic dissimilatory phosphite oxidation, an extremely efficient concept of microbial electron economy.
Environmental Microbiology. DOI: 10.1111/1462-2920.16470
Avasthi I., H. Lerner, J. Grings, C. Gräber, D. Schleheck* and H. Cölfen*. 2023.
Biodegradable mineral plastics.
Small Methods 19: e2300575. DOI: 10.1002/smtd.202300575
Eck, M., S.T. Schwab, T.F. Nelson, K. Wurst, S. Iberl, D. Schleheck, C. Link, G. Battagliarin and S. Mecking. 2023.
Biodegradable high-density polyethylene-like material.
Angewandte Chemie Int. Ed. Engl. 62: e202213438. DOI: 10.1002/anie.202213438.
2022
Ibrahim, A., S. Hoeckendorff, D. Schleheck, L. Epp, M. van Kleunen and A. Meyer. 2022.
Vegetation changes over the last centuries in the Lower Lake Constance region reconstructed from sediment‐core environmental DNA.
Environmental DNA 4: 830-845. DOI: 10.1002/edn3.292
Schaller, S., M.E. Böttcher, M.W. Buechi, L.S. Epp, S.C. Fabbri, N. Gribenski, U. Harms, S. Krastel, A. Liebezeit, K. Lindhorst, H. Marxen, U. Raschke, D. Schleheck, I. Schmiedinger, A. Schwalb, H. Vogel, M. Wessels and F.S. Anselmetti. 2022.
Postglacial evolution of Lake Constance: sedimentological and geochemical evidence from a deep-basin sediment core.
Swiss Journal of Geosciences 115: 7. DOI: 10.1016/j.tecto.2020.228708
2021
Mao, Z., F. Grässle, J. Frey, P. Franchini, D. Schleheck, N. Müller and B. Schink. 2021.
Phosphitispora fastidiosa gen. nov. sp. nov., a new dissimilatory phosphite-oxidizing anaerobic bacterium isolated from anaerobic sewage sludge.
International Journal of Systematic and Evolutionary Microbiology 71: 005142. DOI: 10.1099/ijsem.0.005142
Burrichter, A.G., S. Dörr, P. Bergmann, S. Haiss, A. Keller, C. Fournier, P. Franchini, E. Isono and D. Schleheck. 2021.
Bacterial microcompartments for isethionate desulfonation in the taurine-degrading human-gut bacterium Bilophila wadsworthia.
BMC Microbiology 21: 340. DOI: 10.1186/s12866-021-02386-w
Fournier, C., E. Riehle, D.R. Dietrich* and D. Schleheck*. 2021.
Is toxin-producing Planktothrix sp. an emerging species in Lake Constance?
Toxins 13: 666. DOI: 10.3390/toxins13090666
Gräßle, F., C. Plugge, P. Franchini, B. Schink, D. Schleheck and N. Müller. 2021.
Pelorhabdus rhamnosifermentans gen. nov., sp. nov., a strictly anaerobic rhamnose degrader from freshwater lake sediment.
Systematic and Applied Microbiology 44: 126225. DOI: 10.1016/j.syapm.2021.126225
Atashgahi, S., M.J. Oosterkamp, P. Peng, J. Frank, B. Kraft, B. Hornung, D. Schleheck, S. Lücker, M.S.M. Jetten, A.J.M. Stams and H. Smidt. 2021.
Proteogenomic analysis of Georgfuchsia toluolica revealed unexpected concurrent aerobic and anaerobic toluene degradation.
Environmental Microbiology Reports 13: 841-851. DOI: 10.1111/1758-2229.12996
Hanson, B., K. Kits, J. Löffler, A. Burrichter, A.W. Fiedler, K. Denger, B. Frommeyer, C. Herbold, T. Rattei, N. Karcher, N. Segata, D. Schleheck* and A. Loy*. 2021.
Sulfoquinovose is a select nutrient of prominent bacteria and a source of hydrogen sulfide in the human gut.
ISME Journal 15: 2779-2791. DOI: 10.1038/s41396-021-00968-0
2020
Frommeyer, B., A.W. Fiedler, S.R. Oehler, B.T. Hanson, A. Loy, P. Franchini, D. Spiteller and D. Schleheck. 2020.
Environmental and intestinal phylum Firmicutes bacteria metabolize the plant sugar sulfoquinovose via a 6-deoxy-6-sulfofructose transaldolase pathway.
iScience 23. DOI: 10.1016/j.isci.2020.101510
Ibrahim, A., E. Capo, M. Wessels, I. Martin, A. Meyer, D. Schleheck* and L.S. Epp*. 2020.
Anthropogenic impact on the historical phytoplankton community of Lake Constance reconstructed by multimarker analysis of sediment‐core environmental DNA.
Molecular Ecology 30. DOI: 10.1111/mec.15696
Poh, W.-H., J. Lin, B. Colley, N. Müller, B.C. Goh, D. Schleheck, A. El Sahili, A. Marquardt, Y. Liang, S. Kjelleberg, J. Lescar, S.A. Rice and J. Klebensberger. 2020.
The SiaABC threonine phosphorylation pathway controls biofilm formation in response to carbon availability in Pseudomonas aeruginosa.
PloS ONE 15: e0241019. DOI: 10.1371/journal.pone.0241019
2019
Atashgahi, S., P. Peng, T. Goris, Y. Lu, B. Nijsse, A. Burrichter, D. Schleheck, J. Koehorst, J. Liu, D. Sipkema, J.S. Damste, F. Stams, M. Häggblom, and H. Smidt. 2019.
Organohalide-respiring Desulfoluna species isolated from marine environments.
ISME Journal 14: 815-827. DOI: 10.1038/s41396-019-0573-y
Peck, S.C., K. Denger, A. Burrichter, S.M. Irwin, E.P. Balskus*, and D. Schleheck*. 2019.
A glycyl radical enzyme enables hydrogen sulfide production by the human intestinal bacterium Bilophila wadsworthia.
PNAS 116: 3171-3176. DOI: 10.1073/pnas.1815661116
Shimada, T., K. Yamamoto, M. Nakano, H. Watanabe , D. Schleheck, and A. Ishihama. 2019.
Regulatory role of CsqR (YihW) in transcription of the genes for catabolism of the anionic sugar sulfoquinovose (SQ) in Escherichia coli K-12.
Microbiology 165: 78-89. DOI: 10.1099/mic.0.000740
2018
Knorr, S., M. Sinn, R. Williams, D. Galetskiy, C. Wang, N. Müller, O. Mayans, D. Schleheck, and J.S. Hartig. 2018.
Wide-spread bacterial lysine degradation proceeding via glutarate and L-2-hydroxyglutarate.
Nature Communications 9: 5071. DOI: 10.1038/s41467-018-07563-6
Burrichter, A., K. Denger, P. Franchini, T. Huhn, N. Müller, D. Spiteller and D. Schleheck. 2018.
Anaerobic degradation of the plant sugar sulfoquinovose concomitant with H2S production: Escherichia coli K-12 and Desulfovibrio sp. strain DF1 as co-culture model.
Frontiers Microbiology 27: 2792. DOI: 10.3389/fmicb.2018.02792
Kunkel, M., L. Zeyffert, S. Schildknecht, K. Boldt, D. Schleheck, M. Leist, and S. Polarz. 2018.
Increasing the resistance of living cells against oxidative stress by non-natural surfactants as membrane guards.
ACS Applied Materials & Interfaces 10: 23638-23646. DOI: 10.1021/acsami.8b07032
Frey, J., F. Schneider, T. Huhn, D. Spiteller, B. Schink and D. Schleheck. 2018.
Two enzymes of the acetone degradation pathway of Desulfococcus biacutus: coenzyme B12-dependent 2-hydroxyisobutyryl-CoA mutase and 3-hydroxybutyryl-CoA dehydrogenase.
Environmental Microbiology Reports 10: 283-292. DOI: 10.1111/1758-2229.12637
2016
Frey, J., H. Rusche, B. Schink and D. Schleheck. 2016.
Cloning, functional expression and characterization of a bifunctional 3-hydroxybutanal dehydrogenase /reductase involved in acetone metabolism by Desulfococcus biacutus.
BMC Microbiology 16: 280. DOI: 10.1186/s12866-016-0899-9
Gehring, J., B. Trepka, N. Klinkenberg, H. Bronner, D. Schleheck and S. Polarz. 2016.
Sunlight-triggered nanoparticle synergy: Teamwork of reactive oxygen species and nitric oxide released from mesoporous organosilica with advanced antibacterial activity.
Journal of the American Chemical Society 138: 3076-3084. DOI: 10.1021/jacs.5b12073
Buhmann, M., B. Schulze, A. Förderer, D. Schleheck and P.G. Kroth. 2016.
Bacteria may induce the secretion of mucine-like proteins by the diatom Phaeodactylum tricornutum.
Journal of Phycology 52: 463-474. DOI: 10.1111/jpy.12409
2015
Felux, A.-K., D. Spiteller, J. Klebensberger and D. Schleheck. 2015.
Entner-Doudoroff pathway for sulfoquinovose degradation in Pseudomonas putida SQ1.
PNAS 112: E4205-4305. DOI: 10.1073/pnas.150704911
Felux, A.-K., P. Franchini and D. Schleheck. 2015.
Permanent draft genome sequence of sulfoquinovose degrading Pseudomonas putida strain SQ1.
SIGS 10:42. DOI: 10.1186/s40793-015-0033-x
2014
Denger, K, M. Weiss, A.-K. Felux, A. Schneider, C. Mayer, D. Spiteller, T. Huhn, A.M. Cook and D. Schleheck. 2014.
Sulfoglycolysis in Escherichia coli K-12 closes a gap in the biogeochemical sulfur cycle.
Nature 507: 114-117. DOI: 10.1038/nature12947
Schmidt, A., M. Frensch, D. Schleheck, B. Schink and N. Müller. 2014.
Degradation of acetaldehyde and its precursors by Pelobacter carbinolicus and P. acetylenicus.
PLoS ONE 9: e115902. DOI: 10.1371/journal.pone.0115902
Ballestriero, F., M. Daim, A. Penesyan, J. Nappi, D. Schleheck, P. Bazzicalupo, E. Di Schiavi and S. Egan. 2014.
Antinematode activity of violacein and the role of the insulin/IGF-1 pathway in controlling violacein sensitivity in Caenorhabditis elegans.
PLoS ONE 9: e109201. DOI: 10.1371/journal.pone.0109201
Gehring, J., D. Schleheck, B. Trepka and S. Polarz. 2014.
Mesoporous organosilica nanoparticles containing superacid and click functionalities leading to cooperativity in biocidal coatings.
ACS Applied Materials & Interfaces 7: 1021-1029. DOI: 10.1021/am5083057
Gutiérrez Acosta, O.B., D. Schleheck and B. Schink. 2014.
Acetone utilization by sulfate-reducing bacteria: draft genome sequence of Desulfococcus biacutus and a proteomic survey of acetone-inducible proteins.
BMC Genomics 15: 584. DOI: 10.1186/1471-2164-15-584
2013
Gehring, J, D. Schleheck, M. Luka and S. Polarz. 2013.
Aerosol-synthesis of mesoporous organosilica nanoparticles with highly reactive, superacidic surfaces comprising sulfonic acid entities.
Adv Functional Materials 24: 1140-1150. DOI: 10.1002/adfm.201302330
Weiss, M., A.I. Kesberg, K.M. LaButti, S. Pitluck, D. Bruce, L. Hauser, A. Copeland, T. Woyke, S. Lowry, S. Lucas, M. Land, L. Goodwin, S. Kjelleberg, A.M. Cook, M. Buhmann, T. Thomas and D. Schleheck. 2013.
Permanent draft genome sequence of Comamonas testosteroni KF-1.
SIGS 8. DOI: 10.4056/sigs.3847890
Felux, A.-K., K. Denger, M. Weiss, A.M. Cook and D. Schleheck. 2013.
Paracoccus denitrificans PD1222 utilizes hypotaurine via transamination followed by spontaneous desulfination to yield acetaldehyde, and finally acetate for growth.
J Bacteriol 195: 2921-2930. DOI: 10.1128/jb.00307-13
Kleinteich, J., S. Wood, J. Puddick, D. Schleheck, F.C. Küpper and D. Dietrich. 2013.
Potent toxins in Arctic environments – presence of saxitoxins and of an unusual microcystin variant in Arctic freshwater ecosystems.
Chemico-Biol Interact 206: 423-431. DOI: 10.1016/j.cbi.2013.04.011
Kesberg, A.I., and D. Schleheck. 2013.
Improved protocol for recovery of bacterial DNA from water filters: sonication and backflushing of commercial syringe filters.
J Microbiol Methods 93: 55-57. DOI: 10.1016/j.mimet.2013.02.001
Schmidt, A., N. Müller, B. Schink and D. Schleheck. 2013.
A proteomic view at the biochemistry of syntrophic butyrate oxidation in Syntrophomonas wolfei.
PLoS ONE 8: e56905. DOI: 10.1371/journal.pone.0056905
2012
Weiss, M., K. Denger, T. Huhn and D. Schleheck. 2012.
Two enzymes of a complete degradation pathway for linear alkylbenzenesulfonate (LAS) surfactants: 4-sulfoacetophenone Baeyer-Villiger monooxygenase and 4-sulfophenylacetate esterase in Comamonas testosteroni KF-1.
Appl Environ Microbiol 78: 8254-8263. DOI: 10.1128/AEM.02412-12
Huynh T.T., D. McDougald, J. Klebensberger, B. Al Qarni , N. Barraud, S.A. Rice, S. Kjelleberg and D. Schleheck. 2012.
Glucose starvation-induced dispersal of Pseudomonas aeruginosa biofilms is cAMP and energy dependent.
PLoS ONE 7: e42874. DOI: 10.1371/journal.pone.0042874
Mayer J., K. Denger, K. Hollemeyer, D. Schleheck and A.M. Cook. 2012.
(R)-Cysteate-nitrogen assimilation by Cupriavidus necator H16 with excretion of 3-sulfolactate: a patchwork pathway.
Arch Microbiol 194: 949-957. DOI: 10.1007/s00203-012-0825-y
Krejčík Z, D. Schleheck, K. Hollemeyer and A.M. Cook. 2012.
A five-gene cluster involved in utilization of taurine-nitrogen and excretion of sulfoacetaldehyde
by Acinetobacter radioresistens SH164.
Arch Microbiol 194: 857-863. DOI: 10.1007/s00203-012-0806-1
Denger, K., T. Huhn, K. Hollemeyer, D. Schleheck and A.M. Cook. 2012.
Sulfoquinovose degraded by pure cultures of bacteria with release of C3-organosulfonates: complete degradation in two-member communities.
FEMS Lett 328: 39-45. DOI: 10.1111/j.1574-6968.2011.02477.x
Buhmann, M., P.G. Kroth and D. Schleheck. 2012.
Photoautotrophic–heterotrophic biofilm communities: a laboratory incubator designed for growing axenic diatoms and bacteria in defined mixed-species biofilms.
Environ Microbiol Reports 4: 133-140. DOI: 10.1111/j.1758-2229.2011.00315.x
2011 - 2000
Schleheck, D., M. Weiss, S. Pitluck, D. Bruce, M.L. Land, S. Han, R. Tapia, C.C.C. Detter, T. Brettin, J. Han, T. Woyke, L. Goodwin, P. Pennacchio, M. Nolan, A.M. Cook, S. Kjelleberg and T. Thomas. 2011.
Complete genome sequence of Parvibaculum lavamentivorans type strain (DS-1T).
SIGS 5. DOI: 10.4056/sigs.2215005
Schleheck, D., F. von Netzer, T. Fleischman, D. Rentsch, T. Huhn, A.M. Cook and H.-P.E. Kohler. 2010.
The missing link in LAS surfactant degradation: 4-sulfoacetophenone as a transient intermediate in the degradation of 3-(4-sulfophenyl)butyrate by Comamonas testosteroni KF-1.
Appl Environ Microbiol 76: 196-202. DOI: 10.1128/AEM.02181-09
Ruff, J., T.H. Smits, A.M. Cook and D. Schleheck. 2010.
Identification of two vicinal operons for the degradation of 2-aminobenzenesulfonate encoded on plasmid pSAH in Alcaligenes sp. strain O-1.
Microbiol Res 165: 288-299. DOI: 10.1016/j.micres.2009.05.006
Barraud, N., D. Schleheck, J. Klebensberger, J.S. Webb, D.J. Hassett, S.A. Rice and S. Kjelleberg. 2009.
Nitric oxide signaling in Pseudomonas aeruginosa biofilms mediates phosphodiesterase activity, decreased cyclic diguanosine-monophosphate levels and enhanced dispersal.
J Bacteriol 191: 7333-7342. DOI: 10.1128/JB.00975-09
Müller, N., D. Schleheck and B. Schink. 2009.
Involvement of NADH:acceptor oxidoreductase and butyryl-CoA dehydrogenase in reversed electron transport during syntrophic butyrate oxidation by Syntrophomonas wolfei.
J Bacteriol 191: 6167-6177. DOI: 10.1128/jb.01605-08
Schleheck, D., N. Barraud, J. Klebensberger, J.S. Webb, D. McDougald, S.A. Rice and S. Kjelleberg. 2009.
Pseudomonas aeruginosa PAO1 preferentially grows as aggregates in liquid batch cultures and disperses upon starvation.
PLoS ONE 4: e5513. DOI: 10.1371/journal.pone.0005513
Thomas, T., F.F. Evans, D. Schleheck, A. Mai-Prochnow, C. Burke, A. Penesyan, D.S. Dalisay, S. Stelzer-Braid, N. Saunders,
J. Johnson, S. Ferriera, S. Kjelleberg and S. Egan. 2008.
Analysis of the Pseudoalteromonas tunicata genome reveals properties of a surface-associated life style in the marine environment.
PLoS ONE 3: e3252. DOI: 10.1371/journal.pone.0003252
James, D.L., R. Cord-Ruwisch, D. Schleheck, M.J. Lee and M. Manefield. 2008.
Cyanocobalamin enables activated sludge bacteria to dechlorinate hexachloro-1,3-butadiene to nonchlorinated gases.
Bioremediation J 12: 177-184. DOI: 10.1080/10889860802477085
Rösch, V., K. Denger, D. Schleheck, T.H. Smits and A.M. Cook. 2008.
Different bacterial strategies to degrade taurocholate.
Arch Microbiol 190: 11-18. DOI: 10.1007/s00203-008-0357-7
Denger, K., S. Weinitschke, T.H. Smits, D. Schleheck and A.M. Cook. 2008.
Bacterial sulfite dehydrogenases in organotrophic metabolism: separation and identification in Cupriavidus necator H16 and in Delftia acidovorans SPH-1.
Microbiology 154: 256-263. DOI: 10.1099/mic.0.2007/011650-0
Schleheck, D., T.P. Knepper, P. Eichhorn and A.M. Cook. 2007.
Parvibaculum lavamentivorans DS-1T degrades centrally substituted congeners of commercial linear alkylbenzenesulfonate to sulfophenyl carboxylates and sulfophenyl dicarboxylates.
Appl Environ Microbiol 73: 4725-4732. DOI: https://doi.org/10.1128/AEM.00632-07
Low, A., D. Schleheck, M. Khou, V. Agaard, M. Lee and M. Manefield. 2007.
Options for in situ remediation of soil contaminated with a mixture of perchlorinated compounds.
Bioremediation J 11: 113-124. DOI: 10.1080/10889860701548556
Schleheck, D. and A.M. Cook. 2005.
Omega-oxygenation of the alkyl sidechain of linear alkylbenzenesulfonate (LAS) surfactant in Parvibaculum lavamentivoransT.
Arch Microbiol 183: 369-377. DOI: 10.1007/s00203-005-0002-7
Denger, K., J. Ruff, D. Schleheck and A.M. Cook. 2004.
Rhodococcus opacus expresses the xsc gene to utilize taurine as a carbon source or as a nitrogen source but not as a sulfur source.
Microbiology 150: 1859-1867. DOI: 10.1099/mic.0.27077-0
Dong, W., P. Eichhorn, S. Radajewski, D. Schleheck, K. Denger, T. P. Knepper, J.C. Murrell and A.M. Cook. 2004.
Parvibaculum lavamentivorans converts linear alkylbenzenesulphonate surfactant to sulphophenylcarboxylates, alpha,beta-unsaturated sulphophenylcarboxylates and sulphophenyldicarboxylates, which are degraded in communities.
J Appl Microbiol 96: 630-640. DOI: 10.1111/j.1365-2672.2004.02200.x
Schleheck, D., T. P. Knepper, K. Fischer and A.M. Cook. 2004.
Mineralization of individual congeners of linear alkylbenzenesulfonate by defined pairs of heterotrophic bacteria.
Appl Environ Microbiol 70: 4053-4063. DOI: 10.1128/AEM.70.7.4053-4063.2004
Schleheck, D., B. J. Tindall, R. Rossello-Mora and A.M. Cook. 2004.
Parvibaculum lavamentivorans gen. nov., sp. nov., a novel heterotroph that initiates catabolism of linear alkylbenzenesulfonate.
Int J Syst Evol Microbiol 54: 1489-1497. DOI: 10.1099/ijs.0.03020-0
Schleheck, D., M. Lechner, R. Schonenberger, M. J. Suter and A.M. Cook. 2003.
Desulfonation and degradation of the disulfodiphenylethercarboxylates from linear alkyldiphenyletherdisulfonate surfactants.
Appl Environ Microbiol 69: 938-944. DOI: 10.1128/AEM.69.2.938-944.2003
Schleheck, D. and A.M. Cook. 2003.
Saccharin as a sole source of carbon and energy for Sphingomonas xenophaga SKN.
Arch Microbiol 179: 191-196. DOI: 10.1007/s00203-002-0515-2
Dong, W., S. Schulz, D. Schleheck and A.M. Cook. 2002.
Characterised reactions in aerobic and anaerobic utilisation of linear alkylbenzenesulfonate (LAS).
In S. N. Agathos and W. Reineke (ed.), Biotechnology for the environment: strategy and fundamentals, vol. 3A, 177-184. Kluwer Academic, Dordrecht.
Schleheck, D., W. Dong, K. Denger, E. Heinzle and A.M. Cook. 2000.
An alpha-proteobacterium converts linear alkylbenzenesulfonate surfactants into sulfophenylcarboxylates and linear alkyldiphenyletherdisulfonate surfactants into sulfodiphenylethercarboxylates.
Appl Environ Microbiol 66: 1911-1916. DOI: 10.1128/AEM.66.5.1911-1916.2000