Publications in 2016

  1. Frey J, Rusche H, Schink B, Schleheck D. Cloning, functional expression and characterization of a bifunctional 3-hydroxybutanal dehydrogenase /reductase involved in acetone metabolism by Desulfococcus biacutus. BMC Microbiol. 2016 Nov 25;16(1):280. PubMed PMID: 27884109; PubMed Central PMCID: PMC5123277.
  2. Junghare M, Spiteller D, Schink B. Enzymes involved in the anaerobic degradation of ortho-phthalate by the nitrate-reducing bacterium Azoarcus sp strain PA01. Environ Microbiol. 2016 Sep;18(9):3175-88. PubMed PMID: 27387486.
  3. Buhmann MT, Schulze B, Förderer A, Schleheck D, Kroth PG. Bacteria may induce the secretion of mucin-like proteins by the diatom Phaeodactylum tricornutum. J Phycol. 2016 Jun;52(3):463-74. PubMed PMID: 26993172.
  4. de Roo T, Huber S, Mecking S. CdSe/CdS-Conjugated Polymer Core-Shell Hybrid Nanoparticles by a Grafting-From Approach. ACS Macro Lett.. 2016; 5:786 - 789.

Publications in 2015

  1. Mortensen F, Schneider D, Barbic T, Sladewska-Marquardt A, Kühnle S, et al. Role of ubiquitin and the HPV E6 oncoprotein in E6AP-mediated ubiquitination. Proc Natl Acad Sci U S A. 2015 Aug 11;112(32):9872-7. PubMed PMID: 26216987; PubMed Central PMCID: PMC4538620.
  2. Felux AK, Spiteller D, Klebensberger J, Schleheck D. Entner-Doudoroff pathway for sulfoquinovose degradation in Pseudomonas putida SQ1. Proc Natl Acad Sci U S A. 2015 Aug 4;112(31):E4298-305. PubMed PMID: 26195800; PubMed Central PMCID: PMC4534283.
  3. Kastl J, Braun J, Prestel A, Möller HM, Huhn T, et al. Mad2 Inhibitor-1 (M2I-1): A Small Molecule Protein-Protein Interaction Inhibitor Targeting the Mitotic Spindle Assembly Checkpoint. ACS Chem Biol. 2015 Jul 17;10(7):1661-6. PubMed PMID: 25978000.
  4. Hegedüs R, Pauschert A, Orbán E, Szabó I, Andreu D, et al. Modification of daunorubicin-GnRH-III bioconjugates with oligoethylene glycol derivatives to improve solubility and bioavailability for targeted cancer chemotherapy. Biopolymers. 2015 May;104(3):167-77. PubMed PMID: 25753049.
  5. Bialas J, Groettrup M, Aichem A. Conjugation of the ubiquitin activating enzyme UBE1 with the ubiquitin-like modifier FAT10 targets it for proteasomal degradation. PLoS One. 2015 Mar 13;10(3):e0120329. PubMed PMID: 25768649; PubMed Central PMCID: PMC4359146.
  6. Erath S, Groettrup M. No evidence for immunoproteasomes in chicken lymphoid organs and activated lymphocytes. Immunogenetics. 2015 Jan;67(1):51-60. PubMed PMID: 25403261.

Publications in 2014

  1. Schmidt A, Frensch M, Schleheck D, Schink B, Müller N. Degradation of acetaldehyde and its precursors by Pelobacter carbinolicus and P acetylenicus. PLoS One. 2014 Dec 23;9(12):e115902. PubMed PMID: 25536080; PubMed Central PMCID: PMC4275255.
  2. Gutiérrez Acosta OB, Schleheck D, Schink B. Acetone utilization by sulfate-reducing bacteria: draft genome sequence of Desulfococcus biacutus and a proteomic survey of acetone-inducible proteins. BMC Genomics. 2014 Jul 11;15:584. PubMed PMID: 25012398; PubMed Central PMCID: PMC4103992.
  3. Schreier VN, Pethő L, Orbán E, Marquardt A, Petre BA, et al. Protein expression profile of HT-29 human colon cancer cells after treatment with a cytotoxic daunorubicin-GnRH-III derivative bioconjugate. PLoS One. 2014 Apr 9;9(4):e94041. PubMed PMID: 24718594; PubMed Central PMCID: PMC3981732.
  4. Aichem A, Catone N, Groettrup M. Investigations into the auto-FAT10ylation of the bispecific E2 conjugating enzyme UBA6-specific E2 enzyme 1. FEBS J. 2014 Apr;281(7):1848-59. PubMed PMID: 24528925.
  5. Denger K, Weiss M, Felux AK, Schneider A, Mayer C, et al. Sulphoglycolysis in Escherichia coli K-12 closes a gap in the biogeochemical sulphur cycle. Nature. 2014 Mar 6;507(7490):114-7. PubMed PMID: 24463506.
  6. de Roo T, Haase J, Keller J, Hinz C, Schmid M, et al. A Direct Approach to Organic/Inorganic Semiconductor Hybrid Particles via Functionalized Polyfluorene Ligands. Adv. Funct. Mater.. 2014; 24:2714 - 2719.

Publications in 2013

  1. Schneider D, Schneider T, Rösner D, Scheffner M, Marx A. Improving bioorthogonal protein ubiquitylation by click reaction. Bioorg Med Chem. 2013 Jun 15;21(12):3430-5. PubMed PMID: 23611767.
  2. Schmidt MJ, Summerer D. Red-light-controlled protein-RNA crosslinking with a genetically encoded furan. Angew Chem Int Ed Engl. 2013 Apr 22;52(17):4690-3. PubMed PMID: 23512703.
  3. Schreier VN, Mező G, Orbán E, Dürr C, Marquardt A, et al. Synthesis, enzymatic stability and in vitro cytostatic effect of Daunorubicin-GnRH-III derivative dimers. Bioorg Med Chem Lett. 2013 Apr 1;23(7):2145-50. PubMed PMID: 23434423.
  4. Schmidt A, Müller N, Schink B, Schleheck D. A proteomic view at the biochemistry of syntrophic butyrate oxidation in Syntrophomonas wolfei. PLoS One. 2013;8(2):e56905. PubMed PMID: 23468890; PubMed Central PMCID: PMC3582634

Publications in 2012

  1. Mayer J, Denger K, Hollemeyer K, Schleheck D, Cook AM. (R)-Cysteate-nitrogen assimilation by Cupriavidus necator H16 with excretion of 3-sulfolactate: a patchwork pathway. Arch Microbiol. 2012 Nov;194(11):949-57. PubMed PMID: 22797525.
  2. Aichem A, Kalveram B, Spinnenhirn V, Kluge K, Catone N, et al. The proteomic analysis of endogenous FAT10 substrates identifies p62/SQSTM1 as a substrate of FAT10ylation. J Cell Sci. 2012 Oct 1;125(Pt 19):4576-85. PubMed PMID: 22797925.
  3. Leurs U, Lajkó E, Mező G, Orbán E, Öhlschläger P, et al. GnRH-III based multifunctional drug delivery systems containing daunorubicin and methotrexate. Eur J Med Chem. 2012 Jun;52:173-83. PubMed PMID: 22480495.
  4. Leurs U, Mező G, Orbán E, Öhlschläger P, Marquardt A, et al. Design, synthesis, in vitro stability and cytostatic effect of multifunctional anticancer drug-bioconjugates containing GnRH-III as a targeting moiety. Biopolymers. 2012;98(1):1-10. PubMed PMID: 21509746.

Publications in 2011

  1. Eger S, Castrec B, Hübscher U, Scheffner M, Rubini M, et al. Generation of a mono-ubiquitinated PCNA mimic by click chemistry. Chembiochem. 2011 Dec 16;12(18):2807-12. PubMed PMID: 22052741.
  2. Manea M, Leurs U, Orbán E, Baranyai Z, Öhlschläger P, et al. Enhanced enzymatic stability and antitumor activity of daunorubicin-GnRH-III bioconjugates modified in position 4. Bioconjug Chem. 2011 Jul 20;22(7):1320-9. PubMed PMID: 21668011.
  3. Kühnle S, Kogel U, Glockzin S, Marquardt A, Ciechanover A, et al. Physical and functional interaction of the HECT ubiquitin-protein ligases E6AP and HERC2. J Biol Chem. 2011 Jun 3;286(22):19410-6. PubMed PMID: 21493713; PubMed Central PMCID: PMC3103319.
  4. Schildknecht S, Pape R, Müller N, Robotta M, Marquardt A, et al. Neuroprotection by minocycline caused by direct and specific scavenging of peroxynitrite. J Biol Chem. 2011 Feb 18;286(7):4991-5002. PubMed PMID: 21081502; PubMed Central PMCID: PMC3037611.

Publications in 2010

  1. Eger S, Scheffner M, Marx A, Rubini M. Synthesis of defined ubiquitin dimers. J Am Chem Soc. 2010 Nov 24;132(46):16337-9. PubMed PMID: 21033666.
  2. Holzberger B, Marx A. Replacing 32 proline residues by a noncanonical amino acid results in a highly active DNA polymerase. J Am Chem Soc. 2010 Nov 10;132(44):15708-13. PubMed PMID: 20961065.