Publications
Bodrikov V, Welte C, Wiechers M, Weschenfelder M, Kaur G, Shypitsyna A, Pinzón-Olejua A, Bastmeyer M, Stuermer CAO (2017) Substrate properties of zebrafish Rtn4b/Nogo and axon regeneration in the zebrafish optic nerve. J Comp Neurol. DOI: 10.1002/cne.24253.
Bodrikov V, Pauschert A, Kochlamazashvili G, Stuermer CA (2017) Reggie-1 and reggie-2 (flotillins) participate in Rab11a-dependent cargo trafficking, spine synapse formation and LTP-related AMPA receptor (GluA1) surface exposure in mouse hippocampal neurons. Exp Neurol 289:31-45.
Pinzón-Olejua A, Welte C, Chekuru A, Bosak V, Brand M, Hans S, Stuermer CA (2017) Cre-inducible site-specific recombination in zebrafish oligodendrocytes. Dev Dyn 246:41-49.
Dempwolff F, Schmidt FK, Hervas AB, Stroh A, Rösch TC, Riese CN, Dersch S, Heimerl T, Lucena D, Hülsbusch N, Stuermer CA, Takeshita N, Fischer R, Eckhardt B, Graumann PL (2016) Super Resolution Fluorescence Microscopy and Tracking of Bacterial Flotillin (Reggie) Paralogs Provide Evidence for Defined-Sized Protein Microdomains within the Bacterial Membrane but Absence of Clusters Containing Detergent-Resistant Proteins. PLoS Genet 12:e1006116.
Hülsbusch N, Solis GP, Katanaev VL, Stuermer CA (2015) Reggie-1/Flotillin-2 regulates integrin trafficking and focal adhesion turnover via Rab11a. Eur J Cell Biol 94:531-545.
Welte C, Engel S, Stuermer CA (2015) Upregulation of the zebrafish Nogo-A homologue, Rtn4b, in retinal ganglion cells is functionally involved in axon regeneration. Neural Dev 10:6.
Pinzón-Olejua A, Welte C, Abdesselem H, Málaga-Trillo E, Stuermer CA (2014) Essential roles of zebrafish rtn4/Nogo paralogues in embryonic development. Neural Dev 9:8.
Koch JC, Solis GP, Bodrikov V, Michel U, Haralampieva D, Shypitsyna A, Tönges L, Bähr M, Lingor P, Stuermer CA (2013) Upregulation of reggie-1/flotillin-2 promotes axon regeneration in the rat optic nerve in vivo and neurite growth in vitro. Neurobiol Dis 51:168-176.
Reuter AT, Stuermer CA, Plattner H (2013) Identification, localization, and functional implications of the microdomain-forming stomatin family in the ciliated protozoan Paramecium tetraurelia. Eukaryot Cell 12:529-544.
Solis GP, Hülsbusch N, Radon Y, Katanaev VL, Plattner H, Stuermer CA (2013) Reggies/flotillins interact with Rab11a and SNX4 at the tubulovesicular recycling compartment and function in transferrin receptor and E-cadherin trafficking. Mol Biol Cell 24:2689-2702.
Solis GP, Radon Y, Sempou E, Jechow K, Stuermer CA, Málaga-Trillo E (2013) Conserved roles of the prion protein domains on subcellular localization and cell-cell adhesion. PLoS One 8:e70327.
Solis GP, Schrock Y, Hülsbusch N, Wiechers M, Plattner H, Stuermer CA (2012) Reggies/flotillins regulate E-cadherin-mediated cell contact formation by affecting EGFR trafficking. Mol Biol Cell 23:1812-1825.
Stuermer CA (2012) How reggies regulate regeneration and axon growth. Cell Tissue Res 349:71-77.
Bodrikov V, Solis GP, Stuermer CA (2011) Prion protein promotes growth cone development through reggie/flotillin-dependent N-cadherin trafficking. J Neurosci 31:18013-18025.
Shypitsyna A, Málaga-Trillo E, Reuter A, Stuermer CA (2011) Origin of Nogo-A by domain shuffling in an early jawed vertebrate. Mol Biol Evol 28:1363-1370.
Stuermer CA (2011) Microdomain-forming proteins and the role of the reggies/flotillins during axon regeneration in zebrafish. Biochim Biophys Acta 1812:415-422.
Stuermer CA (2011) Reggie/flotillin and the targeted delivery of cargo. J Neurochem 116:708-713.
Solis GP, Málaga-Trillo E, Plattner H, Stuermer CA (2010) Cellular roles of the prion protein in association with reggie/flotillin microdomains. Front Biosci 15:1075-1085.
Stuermer CA (2010) The reggie/flotillin connection to growth. Trends Cell Biol 20:6-13.
Abdesselem H, Shypitsyna A, Solis GP, Bodrikov V, Stuermer CA (2009) No Nogo66- and NgR-mediated inhibition of regenerating axons in the zebrafish optic nerve. J Neurosci 29:15489-15498.
Diekmann H, Stuermer CA (2009) Zebrafish neurolin-a and -b, orthologs of ALCAM, are involved in retinal ganglion cell differentiation and retinal axon pathfinding. J Comp Neurol 513:38-50.
Hinderhofer M, Walker CA, Friemel A, Stuermer CA, Möller HM, Reuter A (2009) Evolution of prokaryotic SPFH proteins. BMC Evol Biol 9:10.
Ismair MG, Häusler S, Stuermer CA, Guyot C, Meier PJ, Roth J, Stieger B (2009) ABC-transporters are localized in caveolin-1-positive and reggie-1-negative and reggie-2-negative microdomains of the canalicular membrane in rat hepatocytes. Hepatology 49:1673-1682.
Málaga-Trillo E, Solis GP, Schrock Y, Geiss C, Luncz L, Thomanetz V, Stuermer CA (2009) Regulation of embryonic cell adhesion by the prion protein. PLoS Biol 7:e55.
Munderloh C, Solis GP, Bodrikov V, Jaeger FA, Wiechers M, Málaga-Trillo E, Stuermer CA (2009) Reggies/flotillins regulate retinal axon regeneration in the zebrafish optic nerve and differentiation of hippocampal and N2a neurons. Journal of Neuroscience 29:6607-6615.
Schrock Y, Solis GP, Stuermer CA (2009) Regulation of focal adhesion formation and filopodia extension by the cellular prion protein (PrPC). FEBS Lett 583:389-393.
Veith NM, Plattner H, Stuermer CA, Schulz-Schaeffer WJ, Bürkle A (2009) Immunolocalisation of PrPSc in scrapie-infected N2a mouse neuroblastoma cells by light and electron microscopy. Eur J Cell Biol 88:45-63.
Drees C, Stuermer CA, Möller HM, Fritz G (2008) Expression and purification of neurolin immunoglobulin domain 2 from Carrassius auratus (goldfish) in Escherichia coli. Protein Expr Purif 59:47-54.
Katanaev VL, Solis GP, Hausmann G, Buestorf S, Katanayeva N, Schrock Y, Stuermer CA, Basler K (2008) Reggie-1/flotillin-2 promotes secretion of the long-range signalling forms of Wingless and Hedgehog in Drosophila. EMBO J 27:509-521.
Langhorst MF, Jaeger FA, Mueller S, Sven Hartmann L, Luxenhofer G, Stuermer CA (2008) Reggies/flotillins regulate cytoskeletal remodeling during neuronal differentiation via CAP/ponsin and Rho GTPases. Eur J Cell Biol 87:921-931.
Langhorst MF, Reuter A, Jaeger FA, Wippich FM, Luxenhofer G, Plattner H, Stuermer CA (2008) Trafficking of the microdomain scaffolding protein reggie-1/flotillin-2. Eur J Cell Biol 87:211-226.
Langhorst MF, Solis GP, Hannbeck S, Plattner H, Stuermer CA (2007) Linking membrane microdomains to the cytoskeleton: regulation of the lateral mobility of reggie-1/flotillin-2 by interaction with actin. FEBS Lett 581:4697-4703.
Selected Publications between 1984 and 2007
Rajendran L, Masilamani M, Solomon S, Tikkanen R, Stuermer CA, Plattner H, Illges H (2003) Asymmetric localization of flotillins/reggies in preassembled platforms confers inherent polarity to hematopoietic cells. Proc Natl Acad Sci U S A 100:8241-8246.
Stuermer CA, Lang DM, Kirsch F, Wiechers M, Deininger SO, Plattner H (2001) Glycosylphosphatidyl inositol-anchored proteins and fyn kinase assemble in noncaveolar plasma membrane microdomains defined by reggie-1 and -2. Mol Biol Cell 12:3031-3045.
Ott H, Bastmeyer M, Stuermer CA (1998) Neurolin, the goldfish homolog of DM-GRASP, is involved in retinal axon pathfinding to the optic disk. J Neurosci 18:3363-3372.
Lang DM, Lommel S, Jung M, Ankerhold R, Petrausch B, Laessing U, Wiechers MF, Plattner H, Stuermer CA (1998) Identification of reggie-1 and reggie-2 as plasmamembrane-associated proteins which cocluster with activated GPI-anchored cell adhesion molecules in non-caveolar micropatches in neurons. J Neurobiol 37:502-523.
Schulte T, Paschke KA, Laessing U, Lottspeich F, Stuermer CA (1997) Reggie-1 and reggie-2, two cell surface proteins expressed by retinal ganglion cells during axon regeneration. Development 124:577-587.
Kaethner RJ, Stuermer CA (1994) Growth behavior of retinotectal axons in live zebrafish embryos under TTX-induced neural impulse blockade. J Neurobiol 25:781-796.
Paschke KA, Lottspeich F, Stuermer CA (1992) Neurolin, a cell surface glycoprotein on growing retinal axons in the goldfish visual system, is reexpressed during retinal axonal regeneration. J Cell Biol 117:863-875.
Bastmeyer M, Beckmann M, Schwab ME, Stuermer CA (1991) Growth of regenerating goldfish axons is inhibited by rat oligodendrocytes and CNS myelin but not but not by goldfish optic nerve tract oligodendrocytelike cells and fish CNS myelin. J Neurosci 11:626-640.
Vielmetter J, Stuermer CA (1989) Goldfish retinal axons respond to position-specific properties of tectal cell membranes in vitro. Neuron 2:1331-1339.
Stuermer CA (1988) Retinotopic organization of the developing retinotectal projection in the zebrafish embryo. J Neurosci 8:4513-4530.
Stuermer CA, Easter SS, Jr. (1984) Rules of order in the retinotectal fascicles of goldfish. J Neurosci 4:1045-1051.
Easter SS, Jr., Stuermer CA (1984) An evaluation of the hypothesis of shifting terminals in goldfish optic tectum. J Neurosci 4:1052-1063.