General databases for complete reference

Medline (marcel leist): Link to medline ; Google scholar: link here

ResearcherID: D-2133-2010; ORCID ID:

Bibliometric information:

Citations: > 16500; h-index: 68 (Thomson Reuters) / 80 (Google Scholar); Sum of IF: > 1200 (update 01. April 2018)


Selected recent publications (R = review)

Delp J, Gutbier S, al. .. Schreiber F, Bergemann J, Kempa S, Nöh K, Leist M. (2018)                
Stage specific metabolic features of differentiating neurons: implications for toxicant sensitivity  
Toxicol Appl Pharmacol 354, 64-80. doi: 10.1016/j.taap.2017.12.013

Nyffeler J, Chovancova P, Dolde X, Holzer AK, al.., Legler DF, Leist M. (20187)                           
A structureactivity relationship linking non-planar PCBs to functional deficits of neural crest cells: new roles for connexins.                                                                                                               
Arch Toxicol 92, 1225-1247.

Nyffeler J, Dolde X, Krebs A, Pinto-Gil K, Pastor M, Behl M, Waldmann T, Leist M. (2017)                
Combination of multiple neural crest migration assay to identify environmental toxicants from a proof-of-concept chemical library.                                                                                        
Arch Toxicol 91, 3613-3632.

Schildknecht S, Di Monte DA, Pape R, Tieu K, Leist M (2017)                                                      
Tipping points and endogenous determinants of nigrostriatal degeneration by MPTP       
Trends Pharmacol Sci 38, 541-555 (R)

Pallocca G, Nyffeler J, Dolde X,  int al.  Waldmann T, Leist M. (2017)                                                 
Impairment of human neural crest cell migration by prolonged exposure to interferon-beta.           
Arch Toxicol 91, 3385-3402

Efremova L, Chovancova P, Adam M, Gutbier S, Schildknecht S, Leist M (2017)                              
Switching from astrocytic neuroprotection to neurodegeneration by cytokine stimulation.
Arch Toxicol, 91, 231-246

Kleiderman S, Gutbier S, al.  Sá JV, Teixeira AP, Brito C, Alves PM, Leist M. (2016)                  
Conversion of non-proliferating astrocytes into neurogenic neural stem cells: control by FGF2 and IFN-gamma                                                                                                                                      
Stem Cells 34, 2861-2874

Kleiderman S, Sá JV, Teixeira AP, Brito C, Gutbier S, .int. al.., Leist M (2016)                                     
Functional and phenotypic differences of pure populations of stem cell-derived astrocytes and neuronal precursor cells                                            
Glia 64, 695-715

Hoelting L, Klima S, Karreman C, al..., Waldmann T, Leist M (2016)                                              
Stem cell-derived immature human dorsal root ganglia neurons to identify peripheral neurotoxicants                                                                                                                                
Stem Cells Transl Med 5, 476-487

Rempel E*, Hölting L*, Waldmann T, al.. Hengstler JG*, Leist M* (2015)                                     
A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors    
Arch Toxicol 89, 1599-1618

Schildknecht S, Pape R, ... int. al.   Brunner T, Marx A, Möller H, Hiller K, Leist M (2015)                   
Preferential extracellular generation of the active parkinsonian toxicant MPP+ by transporter-independent export of the intermediate MPDP+.
Antioxid Redox Signal 23, 1001-1016

Selected reviews and concept papers:

Bal-Price A, al... Leist M. (2018) Recommendation on test readiness criteria for new approach methods in toxicology: Exemplified for developmental neurotoxicity.
ALTEX. 2018 Feb 23. doi: 10.14573/altex.1712081

Fritsche E, int. al..., Leist M, ...Bal-Price A. (2018). Consensus statement on the need for innovation, transition and implementation of developmental neurotoxicity (DNT) testing for regulatory purposes.                     
Toxicol Appl Pharmacol 354, 3-6. doi: 10.1016/j.taap.2018.02.004.

Terron A, ... EFSA WG EPI1 and its other members, Leist M, Schildknecht S (2018) An adverse outcome pathway for parkinsonian motor deficits associated with mitochondrial complex I inhibition.
Arch Toxicol 92, 41-82

Fritsche E, al..., Leist M, ..., Gourmelon A. (2017) OECD/EFSA workshop on developmental neurotoxicity (DNT): The use of non-animal test methods for regulatory purposes.
ALTEX 34, 311-315

Leist M (2017) New animal-free concepts and test methods for developmental toxicity and peripheral neurotoxicity
Altern Lab Anim 45, 253-260.

Leist M, al... Hengstler JG (2017) Adverse outcome pathways: opportunities, limitations and open questions   
Arch Toxicol 91, 3477-3505

Ockleford C, al..., Leist M, Terron A and Bennekou SH (EFSA Panel on Plant Protection Products and their Residues) (2017). Scientific Opinion on the investigation into experimental toxicological properties of plant protection products having a potential link to Parkinson’s disease and childhood leukaemia.                           
EFSA J 15, 4691, (325 pages) doi:10.2903/j.efsa.2017.4691

Pamies D, al... Leist M, ..., Hartung T. (2017) Good Cell Culture Practice for stem cells and stem-cell-derived models.
ALTEX 34, 95-132

Aschner M, al... Leist M (2017) Reference compounds for alternative test methods to indicate developmental neurotoxicity (DNT) potential of chemicals: example lists and criteria for their selection and use.      
ALTEX 34, 49-74

Schmidt BZ, al.. Leist M, Kobolák J, Dinnyés A (2017) In vitro acute and developmental neurotoxicity screening: an overview of cellular platforms and high-throughput technical possibilities                                   
Arch Toxicol 34, 1-33

Leist M, Jaattela M. (2001). - Four deaths and a funeral: from caspases to alternative mechanisms.
Nature Reviews Mol Cell Biol, 2, 589-598.

Leist M, Künstle G, Gantner F, Wendel A. (1998). - Cytokine-mediated hepatic apoptosis.
Rev Physiol Biochem Pharmacol, 133, 109-155.